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Pulmonary hyalinizing granuloma

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INTRODUCTION: Pulmonary hyalinizing granuloma is a rare, benign lung disease of unknown etiology. It usually manifests as solitary and sometimes as multiple pulmonary nodules. Here we present an unusual case of incidental slow-growing lung mass in a patient Pulmonary hyalinizing granuloma (PHG) is a rare, benign lung disease of unknown etiology. It usually manifests as solitary and sometimes as multiple pulmonary nodules. It may have irregular margins, cavitation, or calcifications mimicking metastasis or primary lung neoplasm Pulmonary hyalinising granulomas are rare, non-infectious, benign fibrosing lesions of the lung that can, sometimes, mimic pulmonary malignancy Lung - nontumor - Hyalinizing granuloma. Tell pathologists your words of wisdom through your free Directory listing, click here and get a personalized webpage

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The pulmonary hyalinizing granuloma (PHG) is defined as benign pulmonary nodules of undetermined etiology and pathogenesis. PHG appear mostly bilateral and multiple in the lung tissue. However, two cases of extrapulmonary manifestation of PHG have been described Pulmonary hyalinising granuloma (PHG) is a rare condition, presenting more often as multiple pulmonary nodules. It is characterized by fibrosing nodules, consisting of central whorled deposits of lamellar collagen. The nodules are benign in their clinical course but may slowly grow in size

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  1. One of the most common causes of lung granulomas is a type of fungal infection known as histoplasmosis. You can develop histoplasmosis by breathing in airborne spores of a fungus normally found in..
  2. Pulmonary hyalinizing granuloma . Title. Learn More Learn More Listen. These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional
  3. The radiological and histological appearance of pulmonary hyalinizing granuloma (PHG) and its pathogenesis are described. The histological features bear a striking resemblance to fibrosing mediastinitis. Patients present clinically with nonspecific respiratory or general symptoms

Pulmonary hyalinizing granuloma is a very rare benign condition. This study describes a case involving pulmonary hyalinizing granuloma in a 76-year-old man who presented with a solitary pulmonary nodule, determined through chest radiography and computed tomography, that mimicked primary lung cancer Pulmonary hyalinizing granuloma is a lesional pattern of pulmonary inflammatory pseudotumor Due to the absence of malignancy, a lung biopsy was performed and showed a pulmonary hyalinizing granuloma (PHG), without signs of malignant degeneration. After 4 months, a follow-up CT was performance showing stability of all the findings Home Pulmonary Lung - Non-Neoplastic Pulmonary Nodules, Depositions & Cysts Pulmonary Hyalinizing Granuloma. slide 4 of 7. Comments: The central portion of the lesion consists entirely of keloidal collagen, ghost remnants of a few fibroblastic cells and few if any inflammatory cells

A pulmonary hyalinising granuloma comprising of a well circumscribed mass made up of thick collagen bundles interspersed by a patchy non-specific chronic inflammatory cell infiltrate (H&E stain, x40). 3. Pulmonary hyalinizing granuloma. Am Rev Respir Dis, 115 (6) (1977) Google Scholar Pulmonary hyalinizing granuloma (PHG) is a rare disease characterized by hyalinized lamellar collagen bundles, usu-ally surrounded by plasma cells, lymphocytes, and histio-cytes (1). Although an immune response to the antigenic stimulation by bacterial infection or autoimmune respons Pulmonary Hyalinizing Granuloma. Home Pulmonary Lung - Non-Neoplastic Pulmonary Nodules, Depositions & Cysts Pulmonary Hyalinizing Granuloma slide 1 of 7. Comments: Some consider hyalinizing granulomas within the morphologic spectrum of inflammatory pseudotumors of the lung, with both lesions behaving in a benign fashion. This low power view. We describe the case of pulmonary hyalinizing granuloma in a 34-year-old asymptomatic man who presented with a pulmonary nodule apparent by chest radiography and computed tomography (CT). He had a history of previous treatment for tuberculosis. His laboratory data were normal Pulmonary hyalinizing granulomas (PHGs) are unusual fibrosclerotic inflammatory lung lesions. The organ-based manifestations of the recently defined IgG4-related sclerosing disease typically show dense fibrosis and heavy lymphoplasmacytic infiltrates. IgG4-related sclerosing disease is also defined by increased serum IgG4 levels and increased.

An open lung biopsy was diagnostic of pulmonary hyalinizing granuloma. This novel association with Aspergillus infection not only expands the spectrum of pathogens linked to pulmonary hyalinizing granuloma but also documents a new pattern of lung disease that can be caused by Aspergillus Pulmonary Hyalinizing granuloma (PHG) is a rare form of lung pathology, often initially presenting as nodules prompting workup for possible malignancy. We present a case of a 29-year-old man with an irregularly shaped, growing hilar mass, suggested to be PHG on initial biopsy, later confirmed by surgical pathology examination of the entire lung. Epub 2016 Dec 11 doi: 10.1177/0218492316684983. PMID: 27940652. Pulmonary hyalinizing granuloma: a multicenter study of 5 new cases and review of the 135 cases of the literature. Lhote R, Haroche J, Duron L, Girard N, Lafourcade MP, Martin M, Begueret H, Taytard A, Capron F, Grenier P, Piette JC, Cohen-Aubart F, Amoura Z Pulmonary hyalinizing granuloma is a rare nonneoplastic fibrosclerosing inflammatory lesion of the lung. The lesion often presents as solitary or multiple lung nodules, which may progress and mimic malignant neoplasm clinically and radiographically (Fig. 1a).The etiology and pathogenesis of the condition is unknown, although many of the patients had autoimmune phenomena or previous exposures. CONCLUSION: Since patients with pulmonary hyalinizing granuloma demonstrated a spectrum of clinical presentations, radiologic changes and histologic features with a variety of associated clinical disorders, pulmonary hyalnizing granuloma is more in keeping with a clinicopathologic entity rather than a specific pathologic disease

6. Yousem SA, Hochholzer L. Pulmonary hyalinizing granuloma. Am J Clin Pathol 1987; 87: 1-6. 7. Yang J, Liang Y, Liao S. Pulmonary hyalinizing granuloma A case report and review of literature. Zhonghua Jie he he huXi za zhi 2001; 24: 369-70. 8. Patel Y, Ishikawa S, MacDonnell KF. Pulmonary hyalinizing granuloma Pulmonary hyalinizing granuloma (PHG) is a rare benign disease of unknown etiology characterized pathologically by deposits of lamellar collagen [1] . PHG was first described in 1977 by Englemann et al. [2] . Clinically, PHG can be asymptomatic (25% of all patients) or present with dry cough, fever, dyspnea and hemoptysis [3] Pulmonary hyalinizing granuloma (PHG) is a rare, benign lung disease of unknown etiology. It usually manifests as solitary and sometimes as multiple pulmonary nodules. It may have irregular margins, cavitation, or calcifications mimicking metastasis or primary lung neoplasm. It should be considered in the differential diagnosis of pulmonary nodules or masses Pulmonary hyalinizing granuloma (PHG) is a rare, self-limited process first described in 19771. Clinical presentation is variable. Symptoms may include nonspecific respiratory complaints or the patient may be asymptomatic. Recurrent, multiple, and often bilateral pulmonary nodules are a characteristic.

Pulmonary hyalinizing granuloma presenting as multiple cavitary calcified nodules. Chest 1991; 100: 1720-1. suggestive of an autoimmune process however a detailed 9. Eschelman DJ, Blickman JG, Lazar HL, O'Keane JC. Schechter M. PHG: a rare autoimmune workup could not be undertaken due to financial cause of solitary pulmonary nodule Pulmonary hyalinizing granuloma - NORD (National Organization for Rare Disorders) Home / For Patients and Families / Rare Disease Information / NIH GARD Report: Pulmonary hyalinizing granuloma

Pulmonary Hyalinizing Granuloma (PHG) is a rare, benign pulmonary nodular lesion of unknown etiology and is characterized pathologically by whorled deposits of lamellar collagen. First described by Engleman et al. [1] in 1977, there have been many descriptions and case reports of this disease; however, most of the case reports have been in. A definitive diagnosis of pulmonary hyalinizing granuloma was made on the basis of these histopathological findings. Although there is no established treatment for pulmonary hyalinizing granuloma, during 1 month of follow-up, posterior uveitis mildly resolved with glucocorticoid treatment and there had been a slight increase in visual acuity In summary, pulmonary hyalinizing granu-loma itself is a rare benign disease and is impor-tant in the differential diagnosis of lung diseases showing multiple pulmonary nodules. The extra-pulmonary involvement is seen in about 20% of the reported cases of PHG. The association of pulmonary hyalinizing granuloma with posterio

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A 41 year-old man with progressive nodular infiltration of the lung of about 2 years'duration died of cardiac and respiratory failure. Autopsy revealed bilateral multiple pulmonary hyalinizing granulomas (PHGs) diagnosed on the basis of the characteristic dense hyaline collagen bundles with nonspecific inflammatory infiltration In 1977, Engleman et al. described pulmonary hyalinizing granuloma (PHG) as a separate entity. 1 This disease is rare and is radiologically characterized by multiple and often bilateral nodules with no preferential localization. 1,2 Its etiology and pathogenesis remain unclear, and a definitive diagnosis is provided by histopathological study of the lesions describing hyalinized lamellar.

Pulmonary Hyalinizing Granuloma and a lymphoprolifera-tive disorder. is rare and is radiologically characterized by multiple and bilateral nodules with no preferential localization.1,2 Its etiology and pathogenesis remain unclear, and a deni-tive diagnosis is provided by histopathological study of the lesion Pulmonary hyalinizing granuloma (PHG) is a rare fibrosclerosing inflammatory lung disease of unknown etiology [].The patient typically presents with cough, chest pain, dyspnea, or hemoptysis in association with multiple bilateral parenchymal nodules [].In 25% of patients the disease is asymptomatic and the nodules are incidentally noted [].Chest radiography and CT reveal relatively large. A granuloma is a small area of inflammation. Granulomas are often found incidentally on an X-ray or other imaging test done for a different reason. Typically, granulomas are noncancerous (benign). Granulomas frequently occur in the lungs, but can occur in other parts of the body and head as well. Granulomas seem to be a defensive mechanism that.

Pulmonary hyalinizing granuloma - PubMe

  1. Pulmonary hyalinizing granulomas are distinct fibrosing lesions of lung, having central whorled deposits of lamellar collagen. Twenty-four cases of this unusual pulmonary lesion are reported herein. Hyalinizing granulomas occur in middle-aged persons and are frequently mistaken for metastatic carcinoma radio- graphically
  2. Pulmonary hyalinizing granuloma: Atypical presentation Cunha, Â.D., Melo, N. and 4 more Open Access Miliary tuberculosis in a rheumatoid arthritis patient receiving long-term tumor necrosis factor monoclonal antibody therap
  3. Pulmonary hyalinizing granuloma is a rare disease. ULBRIGHr et al. found only two cases of PHG in 86 patients with pulmonary granulomas [2]. There is no sex or race predilection. The mean age of presentation is 45 yr. PHG is usually radiologically characterized by multiple and often bilateral nodules without pref­.
  4. Recurrent pulmonary hyalinizing granuloma J Bras Pneumol. 2010;36(5):662-665 665 apparently unrelated to the pulmonary profile. 4. Chalaoui J, Grégoire P, Sylvestre J, Lefebvre R, Amyot R. Pulmonary hyalinizing granuloma: a cause of pulmonary nodules. Radiology. 1984;152(1):23-6. 5. Esme H, Ermis SS, Fidan F, Unlu M, Dilek FH. A cas

Pulmonary Hyalinizing Granuloma Associated with Idiopathic

  1. ed to be a.
  2. Pulmonary hyalinizing granuloma is a rare benign lesion, the etiology and pathogenesis of which have yet to be well defined. (1) Initially described in 1977, pulmonary hyalinizing granuloma presents as multiple, mostly bilateral, recurrent pulmonary nodules that affect patients of both genders with equal frequency
  3. Pulmonary Hyalinizing Granuloma Abstract Send to Citation Mgr. Add to Favorites. Email to a Friend. Track Citations. Pulmonary Hyalinizing Granuloma Philip Engleman . x. Philip Engleman. Search for articles by this author , Averill A. Liebow . x. Averill A. Liebow. Search for articles by this author.
  4. Pulmonary hyalinizing granuloma (PHG) is a rare disease with distinct fibrosing lesions of the lung characterized by central whorled deposits of lamellar collagen. It has been reported that PHG is accompanied by extra-pulmonary fibrous lesions at various sites including the kidney, tonsils and thyroid glands. [1
  5. A case of pulmonary hyalinizing granuloma. Tohoku J Exp Med 1992;167:39-45. 3 Rahatullah A, Waheed Z, Khan JA, et al. Pulmonary hyalinising granuloma: a rare pulmonary disorder. J Pak Med Assoc 2012;62:493-5. 4 Saleem MA, Bhat R, Sinha B. Solitary pulmonary hyalinising granuloma: a rare cause of pulmonary nodule. BJR Case Rep 2017;3.
  6. ick primary or metastatic carcinoma or.
Hyalinizing Granuloma | Basicmedical Key

Pulmonary hyalinizing granuloma (PHG) is a rare benign pulmonary nodular lesion of unknown etiology. We present a case of a 5-year-old boy who was found to have a chest mass while being evaluated for abdominal pain. He underwent a CXR and CT scan that showed popcorn calcifications in the right posterior mediastinum and within the hilum of right. Pulmonary hyalinizing granuloma is a rare disease generally involving a benign lesion, especially in asymptomatic patients. Patients should be assessed for other diseases to confirm presence confined to the lung only, particularly when nodules are disseminated in both lungs Pulmonary hyalinizing granuloma is an uncommon lung disease. Its etiopathogenesis is unknown, although it could be associated with an autoimmune or previous infectious process. The definitive diagnosis is provided by the histopathologic study of the lesion. We describe the case of a patient with a history of tuberculosis and with a pulmonary. F-N: fetal germ cell (pending) giant cell giant cell interstitial pneumonia Goodpasture syndrome granular cell tumor granulomatosis with polyangiitis grossing & features to report hemangioma Herpes simplex histology Histoplasma honeycomb lung hyalinizing granuloma hypersensitivity pneumonitis hypoplasia idiopathic eosinophilic pneumonia.

Pulmonary hyalinizing granuloma: a multicenter study of 5

Pulmonary Hyalinizing Granuloma - CHEST

Pulmonary Hyalinizing Granuloma - CHES

We report a case of pulmonary hyalinizing granuloma (PHG) with laryngeal and subcutaneous involvement. A 43-year-old man was admitted to our hospital for assessment of hoarseness. Cervical and chest computed tomography, respectively, revealed a laryngeal tumor and two pulmonary masses pulmonary hyalinizing granuloma h a z e m a l i 3. CLINICAL • Rare disease • Unknown etiology - May be autoimmune - May be due to pervious exposure to fungal or mycobacterial antigens • Affect adults • Multiple, bilateral, and nodular lesions by CT • Also associated with: - Sclerosing mediastinitis - Retroperitoneal fibrosi Pulmonary Hyalinizing granuloma (PHG) is a rare form of lung pathology, often initially presenting as nodules prompting workup for possible malignancy. We present a case of a 29-year-old man with an irregularly shaped, growing hilar mass, suggested to be PHG on initial biopsy, later confirmed by surgical pathology examination of th

Pulmonary hyalinizing granuloma is a lesion characterized by keloid-like fibrosis in the lung and is not granulomatous. Similarly, radiologists often use the term granuloma when they see a calcified nodule on X-ray or CT scan of the chest. They make this assumption since granulomas usually contain calcium, although the cells that form a. Although these findings are not immediately diagnostic of Varicella pneumonia, they allow for a list of differential diagnosis which includes nodular amyloidosis, calcified metastasis, hyalinizing granuloma, epithelioid hemangioendothelioma, necrobiotic nodules of rheumatoid arthritis, multiple pulmonary chondromas, and progressive massive.

Pulmonary hyalinizing granuloma should be considered in the differential diagnosis of longstanding dysphagia. Abstract A 25-year-old man presented with a 2-month history of dysphagia and past history of pulmonary and intestinal tuberculosis. A barium swallow showed a point of constriction 42 mm above the gastroesophageal junction —Literature and personal review of cases with focus on inflammatory pseudotumors of the lung, organizing pneumonia, nodular lymphoid hyperplasia, apical cap, round atelectasis, and sclerosing mediastinitis with its pulmonary counterpart, hyalinizing granuloma. Conclusions - Multiple hyalinising granuloma of lung - Multiple hyalinizing granuloma of lung - Multiple pulmonary hyalinizing granuloma Hide descriptions. Concept ID: 707370001 Read Codes: ICD-10 Codes: J841 Powered by X-Lab. This tool allows you to search SNOMED CT and is designed for educational use only. The full SNOMED CT. The anatomopathological study was consistent with pulmonary hyalinizing granuloma. In the postoperative period, the patient experienced several episodes of bronchospasm, which was reversible with the use of symptomatic medication. At this writing, the patient was receiving maintenance therapy with prednisone (40 mg/day) and had shown clinical. Looking for an examination copy? This title is not currently available for examination. However, if you are interested in the title for your course we can consider offering an examination copy. To register your interest please contact collegesales@cambridge.org providing details of the course you.

Pulmonary Hyalinizing Granuloma Associated with Idiopathic

Pulmonary Hyalinizing Granuloma: a Rare Cause of Benign

  1. « Pulmonary Hyalinizing Granuloma: A Case Of Progressive Hypoxemic Respiratory Failure Despite Aggressive Immunomodulatory Therapy ». Dans American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California
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  4. Findings were compatible with pulmonary hyalinizing granuloma (PHG). PHG is a rare disease 1,2 that typically occurs in middle-aged patients with non-specific respiratory manifestations or general symptoms. 2 Invasive techniques are necessary for histologic diagnosis. 1 Although the physiopathology of this entity is unclear,.
Pulmonary Hyalinizing Granuloma in the Differential

Video: Pulmonary Hyalinizing Granuloma: A Rare Cause of a Benign

Pulmonary hyalinising granuloma Radiology Reference

Pulmonary hyalinizing granuloma is a very rare benign condition. is study describes a case involving pulmonary hyalinizing granuloma in a 76-year-old man who presented with a solitary pulmonary nodule, determined through chest radiography an Pulmonary hyalinising granuloma (PHG) is a very rare disease first reported in 1964 by Benfield et al. 1 In 1977, Engleman et al. 2 went on to characterise the histology of these lesions as hyalinised lamellar collagen bundles in the presence of plasma cells, lymphocytes and histiocytes. The disease often presents as multiple smooth rounded nodules within the lung parenchyma and can mimic.

Pathology Outlines - Hyalinizing granulom

Natural Course of Pulmonary Hyalinizing Granuloma in a Decade Abstract Send to Citation Mgr. Add to Favorites. Email to a Friend. Track Citations. Natural Course of Pulmonary Hyalinizing Granuloma in a Decade N. Uchida 2. x. N. Uchida . Search for articles by this author, K. Fujita 2. x. K. Fujita. A 52-year-old, asymptomatic patient presented with bilateral lung nodules on chest radiograph. She was diagnosed to have pulmonary hyalinizing granuloma on an open lung biopsy. We review the clinical features of this rare disease A case of pulmonary hyalinising granuloma (PHG) complicated by deep venous thrombosis (DVT) is presented. The DVT was associated with the presence of a lupus anticoagulant. In the past PHG has been linked to various auto-antibodies, but to the best of the authors' knowledge, this is the first case reporting PHG in association with a lupus anticoagulant and clinically significant venous thrombosis

Non-diagnosed pulmonary hyalinizing granuloma (PHG) as a

A 41 year‐old man with progressive nodular infiltration of the lung of about 2 years'duration died of cardiac and respiratory failure. Autopsy revealed bilateral multiple pulmonary hyalinizing granulomas (PHGs) diagnosed on the basis of the characteristic dense hyaline collagen bundles with nonspecific inflammatory infiltration. Constrictive pericarditis, retroperitoneal fibrosis. 1 Engleman P, Liebow AA, Gmelich J, et al. Pulmonary hyalinizing granuloma. Am Rev Respir Dis 1977;115:997-1008. 2 Lhote R, Haroche J, Duron L, et al. Pulmonary hyalinizing granuloma: a multicenter study of 5 new cases and review of the 135 cases of the literature. Immunol Res 2017;65:375-85. 3 Ussavarungsi K, Khoor A, Jolles HI, et al The combination of necrosis with vessel involvement or hyalinized stroma might also suggest Wegener's granulomatosis, pulmonary hyalinizing granuloma and mycobacterial pseudotumor (2). However, the presence of a lytic lesion in the vertebral T10 as well as the marked cytologic atypia present in the spindle cell component seem to support a.

Solitary pulmonary hyalinising granuloma: a rare cause of

They found that 61 (71%) were proven infectious, 3 (3%) were diagnosed as WG (1) and hyalinizing granuloma (2), and 22 (26%) remained unexplained after clinical, radiological and microbiological. Pulmonary Hyalinizing Granuloma (PHG) is a rare, benign pul-monary nodular lesion of unknown etiology and is characterized pathologically by whorled deposits of lamellar collagen. First described by Engleman et al. [1] in 1977, there have been many descriptions and case reports of this disease; however, most of th Pulmonary hyalinizing granuloma manifests radiologically as solitary or multiple nodules with well-defined borders, ranging in size from a few millimeters to 15 cm in diameter [1, 2] (Figs. 13A and 13B). Cavitation is unusual Pulmonary hyalinizing granuloma is a very rare benign condition , which usually manifests as solitary and sometimes as multiple pulmonary nodules. Deposition of immune complexes in the lung parenchyma due to hypersensitivity reactions is implicated in the etiology of pulmonary hyalinizing granuloma Pulmonary Hyalinizing Granuloma in a Veteran with Latent Tuberculosis and Agent Orange Exposure. Author: Jonathan,Dell Pena (1), Jaime Betancourt, MD (2), Scott Oh, DO (2), Michael Lewis, MD (3) (1) UCLA David Geffen School of Medicine (2) UCLA Department of Medicine, Division of Pulmonary and Critical Care (3) Department of Pathology, Greater.

Lung Granuloma: Treatment, Symptoms, Cancer, and Mor

Pulmonary hyalinizing granuloma (PHG) is a rare, benign lung disease that was first described by Engleman et al., in 1977.[1] The disease presents as slowly enlarging solitary or multiple nodules, which can simulate metastatic disease. [2] No gender or racial preference has been shown and reported ag Pulmonary hyalinizing granuloma. Am Rev Respir Dis 1977;115(6):997-1008. Medline, Google Scholar; 35. Schlosnagle DC, Check IJ, Sewell CW, Plummer A, York RM, Hunter RL. Immunologic abnormalities in two patients with pulmonary hyalinizing granuloma

Pulmonary hyalinizing granuloma Genetic and Rare

Pulmonary hyalinizing granuloma with associated elevation in serum and tissue IgG4 occurring in a patient with a history of sarcoidosis. Am J Surg Pathol 2012; 36: 774-8. Dent, RG, Godden, DJ, Stovin, PGI, Stark, JE. Pulmonary hyalinizing granuloma in association with retroperitoneal fibrosis Pulmonary Hyalinizing Granuloma: a Rare Cause of Benign . INTRODUCTION. Pulmonary hyalinizing granuloma (PHG) is a rare, benign lung disease that was first described by Engleman et al., in 1977.[] The disease presents as slowly enlarging solitary or multiple nodules, which can simulate metastatic disease.[ Pulmonary Hyalinizing Granuloma in HIV/AIDS Theresa Liu, Maggy Kyrollos, Stephen Kravcik; Affiliations Theresa Liu Internal Medicine Training Program, University of Ottawa, Ottawa Hospital, Ottawa, Ontario, Canada Maggy Kyrollos Division of Anatomical Pathology, University of Ottawa, Ottawa Hospital, Ottawa, Ontario, Canada. Pulmonary hyalinizing granuloma has rarely been reported and is a benign entity of unknown origin. The chest radiograph reveals multiple and frequently bilateral pulmonary nodules. We describe a patient with pulmonary hyalinizing granuloma who presented with a central mass in the left lung mimicking lung carcinoma

Figure 2 | Hyalinizing Granuloma: An Unusual Case of aPathology 2 > Evans > Flashcards > AUG10201_Evans(PDF) Pulmonary Hyalinizing Granuloma in a Veteran With

Pulmonary hyalinizing granuloma (PHG) and fibrosing mediastinitis (FM) are included together because their histologic findings and pathogenesis are identical. They differ only by site with PHG being confined to the lung parenchyma and FM affecting mainly mediastinal structures although it can extend into the lung causing the appearance of a. Uniportal VATS wedge resection for pulmonary hyalinizing granuloma Dr.İlhan Ocakcıoğlu, Turke Pulmonary hyalinizing granuloma is a rare benign lesion, the etiology and pathogenesis of which have yet to be well defined.(1) Initially described in 1977, pulmonary hyalinizing granuloma presents as multiple, mostly bilateral, recurrent pulmonary nodules that affect patients of both genders with equal frequency.(1